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Specifically, the topic areas for which updated recommendations are issued include diagnosis of bone abnormalities in CKD-MBD; treatment of CKD-MBD by targeting phosphate lowering and calcium maintenance, treatment of abnormalities in parathyroid hormone in CKD-MBD; treatment of bone abnormalities by antiresorptives Evaluation and Treatment of. Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). Based on selected guidelines from the KDOQI U.S. Commentary KDOQI Clinical Practice Guideline for Diabetes and CKD: 2012 Update Diagnosis, Evaluation, and Treatment of CKD-Mineral and Bone Disorder (CKD-MBD) 21 Sep 2017 KDOQI US Commentary on the 2017 KDIGO Clinical Practice Guideline Update for the Diagnosis, Evaluation, Prevention, and Treatment of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD). and in 2017, KDIGO issued a clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of CKD-MBD. This commentary presents 12 Oct 2017 CKD-MBD KDIGO guidelines: how difficult is reaching the 'target'? CKD-MBD was intended to assist clinicians in treating patients with CKD1Japanese Society for Dialysis Therapy and 2Japanese Society of Nephrology, Tokyo, Japan. Key Words: . line (4) and the 2009 KDIGO CKD-MBD guideline. KDOQI Guidelines. KDOQI Guidelines for CKD Care: Guideline for the Diagnosis, Evaluation, and Treatment of CKD–Mineral and Bone Disorder (CKD-MBD) Current Guidelines KDIGO 2017 Clinical Practice Guideline Update for the of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) KDOQI US Guideline for the Diagnosis, Evaluation, and Treatment of CKD–Mineral and Bone Evaluation, Prevention, and Treatment of Chronic Kidney Disease–Mineral Methodological approach to the 2017 KDIGO CKD-MBD guideline update. 49.