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This Handbook outlines in detail Cochrane's methods for conducting Cochrane. Training. Trusted evidence. Informed decisions. Better health. for Systematic Reviews of Interventions is the official guide that describes in For further information and for any Handbook enquiries please contact: methods@cochrane.org. Home > Front page. Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0. [updated March 2011]. Editors: Julian PT Higgins and Sally Standards for conduct and reporting of new intervention reviews. Guidance. Cochrane Style Manual. Guidance. Cochrane Information Specialists' Handbook. GRADE is a systematic approach to rating the certainty of evidence in systematic reviews and other evidence syntheses. Introduction to GRADE. Slidecast.Cochrane Training provides online learning & workshops on evidence-based health care and systematic reviews for authors, editors, patients/consumers